Simon Nazarian

Simon Nazarian serves as City of Hope’s system executive vice president and chief digital and technology officer. Nazarian leads the organization’s overall technology strategy, transforming and expanding technology innovation through digital, AI, and emerging technology initiatives. He is responsible for evolving City of Hope’s technology and digital ecosystem, with the goal of enabling scientific discoveries, enhancing the overall patient and care team experience, and driving commercialization.

A seasoned visionary leader, Nazarian joined City of Hope in 2024 after serving for four years as chief information officer at Optum Health, one of America’s leading healthcare providers and health plans. He brings more than 25 years of experience developing innovative strategies and leading large transformational initiatives for Optum®, McKinsey & Company, Kaiser Permanente, Sony Pictures Entertainment, and other large organizations.